Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01006TIGR00659 family protein; KEGG: bao:BAMF_3670 6.1e-35 lrgB3; anti-holin factor controlling activity of murein hydrolases; Psort location: CytoplasmicMembrane, score: 10.00. (233 aa)    
Predicted Functional Partners:
D920_01007
LrgA family protein; KEGG: btk:BT9727_3424 8.8e-11 holin-like protein K06518; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.999
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.979
D920_01005
M protein trans-acting positive regulator; Psort location: Cytoplasmic, score: 7.50.
     
 0.972
D920_00859
LytTr DNA-binding domain protein; KEGG: ppo:PPM_2376 2.1e-18 lytTr; chemotaxis response regulator protein-glutamate methylesterase 1; Psort location: Cytoplasmic, score: 9.97.
     
 0.956
D920_01425
LytTr DNA-binding domain protein; KEGG: ppo:PPM_2376 1.9e-15 lytTr; chemotaxis response regulator protein-glutamate methylesterase 1; Psort location: Cytoplasmic, score: 9.97.
     
 0.956
gshAB
Glutamate--cysteine ligase/gamma-glutamylcysteine synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
       0.949
msrB
methionine-R-sulfoxide reductase; KEGG: efu:HMPREF0351_10140 2.5e-61 msrB; peptide-methionine (R)-S-oxide reductase K07305; Psort location: Cytoplasmic, score: 7.50.
     
 0.948
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.944
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.935
D920_00809
Hypothetical protein; KEGG: efc:EFAU004_01232 4.4e-286 ysyl-tRNA synthetase K14205; Psort location: CytoplasmicMembrane, score: 10.00.
       0.932
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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