Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
D920_01103Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)    
Predicted Functional Partners:
deoD
KEGG: efu:HMPREF0351_10047 1.5e-102 deoD2; purine-nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.97.
     
 0.999
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
  
  
 0.999
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.998
D920_01101
KEGG: efi:OG1RF_10140 3.9e-150 adh3; putative alcohol dehydrogenase (NADP(+)); Psort location: Cytoplasmic, score: 9.97.
       0.995
D920_01105
Branched-chain amino acid ABC transporter, permease protein; KEGG: mdi:METDI2374 5.3e-36 ABC transporter permease K02057; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family.
       0.994
D920_01106
Branched-chain amino acid ABC transporter, permease protein; KEGG: pfe:PSF113_0699 1.3e-41 ABC transporter permease K02057; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family.
       0.994
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.992
D920_01111
KEGG: efc:EFAU004_00077 3.1e-189 pdp; pyrimidine-nucleoside phosphorylase K00756; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.990
D920_01499
KEGG: efc:EFAU004_02600 6.7e-84 hpt; Hypoxanthine-guanine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.987
D920_01107
ABC transporter, ATP-binding protein; KEGG: efu:HMPREF0351_10042 6.5e-244 ABC superfamily ATP binding cassette transporter, ABC protein K02056; Psort location: CytoplasmicMembrane, score: 9.96.
       0.986
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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