Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
coaAPantothenate kinase; KEGG: efu:HMPREF0351_10035 4.1e-148 coaA; pantothenate kinase K00867; Psort location: Cytoplasmic, score: 7.50. (307 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
       0.995
D920_01113
Methyltransferase small domain protein; KEGG: efu:HMPREF0351_10036 1.8e-90 rsmC; methyltransferase K00564; Psort location: Cytoplasmic, score: 7.50.
 
     0.994
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.985
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
     
 0.981
D920_00015
Topology modulation domain protein.
     
 0.979
D920_01112
KEGG: hor:Hore_04570 1.4e-53 LacI family transcriptional regulator K02529; Psort location: Cytoplasmic, score: 9.97.
  
    0.978
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
 0.975
D920_01108
Basic membrane protein; KEGG: apb:SAR116_1606 1.3e-30 membrane lipoprotein K07335.
       0.974
D920_01109
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.974
D920_01111
KEGG: efc:EFAU004_00077 3.1e-189 pdp; pyrimidine-nucleoside phosphorylase K00756; Psort location: Cytoplasmic, score: 7.50.
       0.974
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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