Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_01117DNA-binding helix-turn-helix protein; KEGG: mla:Mlab_1603 4.4e-12 adenine deaminase K01486; Psort location: Cytoplasmic, score: 7.50. (388 aa)    
Predicted Functional Partners:
D920_01118
Hypothetical protein.
     
 0.998
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.989
D920_00129
Hypothetical protein.
  
  
 0.950
D920_02045
DNA-binding helix-turn-helix protein; KEGG: sgg:SGGBAA2069_c10720 0.0057 transcriptional regulator.
  
  
 0.941
D920_01127
DNA-binding helix-turn-helix protein; KEGG: fnu:FN0522 0.00098 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.936
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.936
D920_02532
Metallo-beta-lactamase domain protein; KEGG: zga:zobellia_1566 0.0040 metallohydrolase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.935
D920_02533
ComEC/Rec2-like protein; KEGG: apb:SAR116_0501 1.0e-06 DNA uptake protein ComEC K02238; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.935
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.933
D920_00549
KEGG: apb:SAR116_1706 4.7e-12 DNA-binding protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.933
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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