Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01121Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (189 aa)    
Predicted Functional Partners:
D920_00135
YD repeat protein; KEGG: phu:Phum_PHUM617500 0.0010 type II transmembrane protein, putative; Psort location: Cellwall, score: 9.20.
  
  
 0.989
D920_01127
DNA-binding helix-turn-helix protein; KEGG: fnu:FN0522 0.00098 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.978
D920_01122
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
  
    0.976
D920_01124
Hypothetical protein; KEGG: edi:EDI_341030 0.00049 intracellular protein transport protein USO1.
  
  
 0.976
D920_01935
DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.970
D920_00503
Replication initiation factor; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.967
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.956
D920_03065
DNA topoisomerase; KEGG: efu:HMPREF0351_10562 0. topB; DNA topoisomerase TopB K03169; Psort location: Cytoplasmic, score: 9.64.
  
  
 0.956
D920_01944
Hypothetical protein.
  
  
 0.948
D920_01512
NlpC/P60 family protein; KEGG: efc:EFAU004_00439 2.9e-46 N-acetylmuramoyl-L-alanine amidase; Psort location: Extracellular, score: 9.98.
  
  
 0.940
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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