Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01155Transcriptional regulator, MerR family; KEGG: rba:RB451 0.0012 site-specific DNA-methyltransferase (cytosine-specific)-transcriptional regulator; Psort location: Cytoplasmic, score: 7.50. (252 aa)    
Predicted Functional Partners:
D920_01153
ABC transporter, ATP-binding protein; KEGG: dca:Desca_0391 7.3e-126 xenobiotic-transporting ATPase K06147; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.999
D920_01154
ABC transporter, ATP-binding protein; KEGG: efi:OG1RF_11766 5.3e-194 multidrug ABC superfamily ATP binding cassette transporter, ABC protein K06147; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.979
D920_00560
Thioredoxin; KEGG: abu:Abu_0457 6.6e-06 hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.974
D920_02214
ABC transporter, ATP-binding protein; KEGG: lbh:Lbuc_2057 3.3e-194 xenobiotic-transporting ATPase K06147; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.958
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.941
D920_01438
KEGG: efc:EFAU004_00692 4.7e-234 glnA; glutamine synthetase, type I K01915; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.939
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.934
pheT
KEGG: efu:HMPREF0351_11283 0. pheT3; phenylalanine--tRNA ligase beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.913
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.910
D920_02032
Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.7e-14 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.909
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.