Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
D920_01197Na+/H+ antiporter; KEGG: cnc:CNE_1c04080 8.6e-27 kdsD; arabinose 5-phosphate isomerase KdsD K03455; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (381 aa)    
Predicted Functional Partners:
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.996
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.992
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
     
 0.991
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.987
D920_03116
Flavodoxin-like protein; KEGG: efc:EFAU004_00485 1.6e-80 NAD(P)H dehydrogenase.
  
 
 0.987
D920_01988
Chloride transporter, ClC family; KEGG: ssr:SALIVB_1179 3.8e-113 ribonuclease HII; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.986
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.985
D920_02831
Putative Na+/H+ antiporter; KEGG: tgo:TGME49_105180 2.4e-17 sodium/hydrogen exchanger, putative; Psort location: CytoplasmicMembrane, score: 10.00.
   
 
 0.981
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.979
D920_02309
KEGG: bya:BANAU_2956 0.00013 ytrA; GntR family transcriptional regulator; Psort location: CytoplasmicMembrane, score: 8.16.
  
  
 0.973
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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