Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01206Site-specific recombinase, phage integrase family; KEGG: bqy:MUS_1239 3.7e-28 ATP synthase C chain (lipid-binding protein)(dicyclohexylcarbodiimide-binding protein); Psort location: Cytoplasmic, score: 7.50; Belongs to the 'phage' integrase family. (388 aa)    
Predicted Functional Partners:
D920_01143
Putative toxin-antitoxin system, toxin component; KEGG: bme:BMEI1683 0.0018 zinc-dependent metallopeptidase K01417; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.955
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.934
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.933
D920_03065
DNA topoisomerase; KEGG: efu:HMPREF0351_10562 0. topB; DNA topoisomerase TopB K03169; Psort location: Cytoplasmic, score: 9.64.
  
  
 0.933
rpsU
Ribosomal protein S21; KEGG: sew:SeSA_A3399 3.0e-10 rpsU; 30S ribosomal protein S21 K02970; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bS21 family.
   
 
 0.911
D920_01127
DNA-binding helix-turn-helix protein; KEGG: fnu:FN0522 0.00098 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
     
 0.910
D920_01935
DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.910
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
 
 0.892
D920_02457
KEGG: efc:EFAU004_01014 1.2e-269 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.892
D920_00793
Pyruvate kinase; KEGG: efc:EFAU004_01291 6.6e-299 Pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.890
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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