Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_01211Hypothetical protein; KEGG: efu:HMPREF0351_10830 6.4e-08 sdhC; succinate dehydrogenase cytochrome b558 subunit; Psort location: CytoplasmicMembrane, score: 9.55. (57 aa)    
Predicted Functional Partners:
D920_01209
Hypothetical protein.
       0.887
D920_01210
DNA binding domain, excisionase family; KEGG: rba:RB5795 2.0e-06 ptsN; PTS system, fructose-specific IIABC component K02806.
       0.773
D920_01212
Hypothetical protein.
       0.757
nfo
Apurinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
      
 0.582
mutM
DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
      
 0.582
D920_01208
Toxin-antitoxin system, antitoxin component, Xre family; KEGG: nsa:Nitsa_1199 5.0e-07 phage repressor; K01356 repressor LexA; Psort location: Cytoplasmic, score: 7.50.
       0.454
D920_01007
LrgA family protein; KEGG: btk:BT9727_3424 8.8e-11 holin-like protein K06518; Psort location: CytoplasmicMembrane, score: 10.00.
      
 0.446
D920_01207
Putative toxin-antitoxin system, toxin component.
       0.438
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
      
 0.403
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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