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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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dltCD-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (77 aa)    
Predicted Functional Partners:
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
 
  
 0.999
D920_01237
Protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
 
 
 0.999
D920_01239
DltD protein.
 
  
 0.999
D920_01235
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
     
 0.997
rpmF
Ribosomal protein L32; KEGG: apb:SAR116_0011 0.00053 50S ribosomal protein L32 K02911; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL32 family.
  
 0.995
D920_01260
KEGG: efu:HMPREF0351_10971 2.7e-119 fabD2; [acyl-carrier-protein] S-malonyltransferase K00645; Psort location: Cytoplasmic, score: 9.97.
  
 0.993
D920_01870
Malonate decarboxylase, epsilon subunit family protein; KEGG: efc:EFAU004_00345 1.6e-137 Malonyl CoA-acyl carrier protein transacylase; K13935 malonate decarboxylase epsilon subunit; Psort location: Cytoplasmic, score: 9.97.
  
 0.993
D920_01258
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.991
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 0.991
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
 0.991
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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