Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
D920_01239DltD protein. (418 aa)    
Predicted Functional Partners:
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
 
  
 0.999
D920_01237
Protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.999
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
  
 0.999
D920_01235
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
     
 0.997
D920_01404
KEGG: efu:HMPREF0351_10747 0. nrdD; incomplete anaerobic ribonucleotide reductase large subunit K00527; Psort location: Cytoplasmic, score: 7.50.
       0.967
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
  
 0.963
acpP-2
Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
  
 0.963
D920_02211
Beta-lactamase; KEGG: efc:EFAU004_02324 1.3e-135 Beta-lactamase; Psort location: CytoplasmicMembrane, score: 9.51.
  
  
 0.953
D920_01956
ABC transporter, permease protein; KEGG: sgg:SGGBAA2069_c14260 2.5e-139 glnH; amino acid ABC transporter amino acid-binding/permease K02029:K02030; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.952
D920_01402
Hypothetical protein; KEGG: efu:HMPREF0351_10749 1.2e-180 ABC superfamily ATP binding cassette transporter, membrane protein K02004; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.949
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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