Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01273Hypothetical protein. (106 aa)    
Predicted Functional Partners:
D920_01271
Phosphocarrier protein HPr; KEGG: efc:EFAU004_01332 5.7e-39 ptsH; phosphocarrier protein HPr K11189; Psort location: Cytoplasmic, score: 10.00.
       0.983
D920_01266
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
     0.971
D920_01272
Negative regulator of genetic competence ClpC/MecB; KEGG: snc:HMPREF0837_11672 4.6e-282 clpE; ATP dependent protease K03697; Psort location: Cytoplasmic, score: 9.89; Belongs to the ClpA/ClpB family.
       0.958
D920_01270
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
       0.922
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.920
D920_02498
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.913
D920_03086
Hydrolase, NUDIX family; KEGG: efu:HMPREF0351_10543 1.1e-76 nudF; ADP-ribose diphosphatase K01515; Psort location: Cytoplasmic, score: 7.50.
       0.902
D920_02660
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
       0.876
D920_02683
Periplasmic binding protein; KEGG: bao:BAMF_3696 1.1e-19 RBAM_035840; iron compound ABC transporter substrate-binding protein FeuA K02016; Psort location: CytoplasmicMembrane, score: 9.68.
       0.876
D920_01697
Negative regulator of genetic competence ClpC/MecB; KEGG: saa:SAUSA300_0510 5.1e-244 clpC; endopeptidase K03696; Psort location: Cytoplasmic, score: 9.95; Belongs to the ClpA/ClpB family.
       0.863
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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