Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_01277Hypothetical protein; KEGG: pfe:PSF113_1419 8.2e-31 yfgO; protein YfgO K03548; Psort location: CytoplasmicMembrane, score: 10.00. (362 aa)    
Predicted Functional Partners:
D920_01278
KEGG: efc:EFAU004_01339 6.5e-54 GNAT family acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.997
D920_01276
Hypothetical protein; KEGG: hpa:HPAG1_1423 7.7e-51 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.995
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
     
 0.994
D920_00809
Hypothetical protein; KEGG: efc:EFAU004_01232 4.4e-286 ysyl-tRNA synthetase K14205; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.970
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.970
D920_01522
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.958
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
     
 0.944
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
  
    0.939
D920_00942
Hypothetical protein; KEGG: hpa:HPAG1_1423 2.1e-71 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 9.96.
     
 0.935
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
       0.933
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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