| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| D920_00538 | D920_01370 | D920_00538 | D920_01370 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | 0.821 |
| D920_00538 | D920_01376 | D920_00538 | D920_01376 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Elongation factor P; KEGG: bpu:BPUM_2177 8.3e-38 efp; elongation factor P K02356; Psort location: Cytoplasmic, score: 9.97. | 0.931 |
| D920_00538 | D920_01377 | D920_00538 | D920_01377 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | 0.888 |
| D920_00538 | argR | D920_00538 | D920_01368 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.402 |
| D920_00538 | folD | D920_00538 | D920_01373 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.904 |
| D920_00538 | nusB | D920_00538 | D920_01374 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.997 |
| D920_00538 | ribA | D920_00538 | D920_00540 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
| D920_00538 | xseA | D920_00538 | D920_01372 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.990 |
| D920_00538 | xseB | D920_00538 | D920_01371 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.826 |
| D920_01370 | D920_00538 | D920_01370 | D920_00538 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.821 |
| D920_01370 | D920_01375 | D920_01370 | D920_01375 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.995 |
| D920_01370 | D920_01376 | D920_01370 | D920_01376 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Elongation factor P; KEGG: bpu:BPUM_2177 8.3e-38 efp; elongation factor P K02356; Psort location: Cytoplasmic, score: 9.97. | 0.993 |
| D920_01370 | D920_01377 | D920_01370 | D920_01377 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | 0.977 |
| D920_01370 | argR | D920_01370 | D920_01368 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.997 |
| D920_01370 | folD | D920_01370 | D920_01373 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.998 |
| D920_01370 | nusB | D920_01370 | D920_01374 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.996 |
| D920_01370 | ribA | D920_01370 | D920_00540 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.694 |
| D920_01370 | xseA | D920_01370 | D920_01372 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.999 |
| D920_01370 | xseB | D920_01370 | D920_01371 | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.999 |
| D920_01375 | D920_01370 | D920_01375 | D920_01370 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family. | 0.995 |