Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01387Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (114 aa)    
Predicted Functional Partners:
rpmA
Ribosomal protein L27; KEGG: pfe:PSF113_5049 1.4e-19 50S ribosomal protein L27 K02899; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.999
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
  
 0.999
D920_01390
KEGG: efu:HMPREF0351_10764 7.1e-80 uracil-DNA glycosylase K02334.
       0.994
D920_01394
Methyltransferase domain protein; KEGG: efc:EFAU004_00735 1.1e-97 O-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
    0.988
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
    0.980
D920_01375
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
    0.975
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
     
 0.969
D920_02412
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.967
D920_01465
Aminotransferase, class V; KEGG: efu:HMPREF0351_12189 8.3e-173 iscS2; pyridoxal phosphate-dependent transferase K04487; Psort location: Cytoplasmic, score: 9.97.
       0.964
D920_01377
Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97.
     
 0.963
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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