Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_01455KEGG: apb:SAR116_2174 1.2e-13 cold-shock DNA-binding domain-containing protein K03704; Psort location: Cytoplasmic, score: 9.97. (66 aa)    
Predicted Functional Partners:
D920_01456
KEGG: apb:SAR116_0666 2.3e-19 DNA repair protein RadC K03630; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0758 family.
     
 0.995
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
     
 0.985
D920_01457
HAD hydrolase, family IA, variant 3; KEGG: efc:EFAU004_02201 1.0e-80 HAD-superfamily hydrolase; Psort location: Cytoplasmic, score: 7.50.
     
 0.962
cshB
DEAD-box ATP-dependent RNA helicase CshB; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.
  
 0.951
cshA
DEAD-box ATP-dependent RNA helicase CshA; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.
  
 0.946
D920_01342
DEAD/DEAH box helicase; KEGG: thl:TEH_16770 6.6e-109 putative RNA helicase; Psort location: Cytoplasmic, score: 9.97.
  
 0.946
D920_02816
DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
  
 
 0.936
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
   
 
 0.921
hpf
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
  
 0.920
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.919
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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