Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa)    
Predicted Functional Partners:
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
  
 0.999
D920_01537
KEGG: lml:lmo4a_0208 1.9e-86 purR; Pur operon transcriptional repressor K09685; Psort location: Cytoplasmic, score: 9.67.
 
  
 0.999
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 0.995
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.994
D920_01538
ABC 3 transport family protein; KEGG: pfe:PSF113_0030 9.4e-30 znuB; protein ZnuB K09816; Psort location: CytoplasmicMembrane, score: 10.00.
       0.993
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.993
D920_00956
Chorismate mutase; KEGG: efc:EFAU004_00196 1.2e-100 maltose O-acetyltransferase K00661; Psort location: Cytoplasmic, score: 9.67.
     
 0.992
D920_01539
ABC transporter, ATP-binding protein; KEGG: efu:HMPREF0351_12583 7.3e-110 zinc ABC superfamily ATP binding cassette transporter, ABC protein K09817; Psort location: CytoplasmicMembrane, score: 8.78.
     
 0.992
D920_01540
ABC transporter, substrate-binding protein; KEGG: saj:SaurJH9_2430 1.2e-38 ribulose-phosphate 3-epimerase K01783; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the bacterial solute-binding protein 9 family.
       0.990
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
  
 0.990
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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