Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01573Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (117 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.981
D920_00375
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.956
D920_01777
Hypothetical protein.
       0.883
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.868
D920_02204
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.802
D920_02205
Hypothetical protein; KEGG: ctp:CTRG_05827 1.2e-09 hypothetical protein; K01183 chitinase; Psort location: Cellwall, score: 9.21.
       0.787
D920_02353
KEGG: llk:LLKF_2194 3.0e-10 yuiD; GNAT family acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.730
D920_01622
KEGG: efc:EFAU004_00597 9.3e-39 MazG nucleotide pyrophosphohydrolase; Psort location: Cytoplasmic, score: 7.50.
       0.721
D920_01577
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.716
mtlD
KEGG: efa:EF0413 7.5e-140 mtlD; mannitol-1-phosphate 5-dehydrogenase; K00009 mannitol-1-phosphate 5-dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
       0.716
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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