Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01581Multidrug resistance protein, SMR family; KEGG: cco:CCC13826_0782 4.2e-11 methionyl-tRNA formyltransferase K11741; Psort location: CytoplasmicMembrane, score: 10.00; overlaps another CDS with the same product name. (105 aa)    
Predicted Functional Partners:
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.967
D920_01579
Nitroreductase family protein; KEGG: efu:HMPREF0351_12619 1.3e-89 NADH dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.966
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.961
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.959
D920_00582
NAD dependent epimerase/dehydratase family protein; KEGG: sud:ST398NM01_0168 4.4e-119 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.950
D920_01312
Glycosyltransferase, group 2 family protein; KEGG: efu:HMPREF0351_10905 0. family 2 glycosyl transferase; Psort location: CytoplasmicMembrane, score: 8.78.
  
  
 0.937
D920_01397
Hypothetical protein; KEGG: zin:ZICARI_096 0.0019 nuoN; putative NADH:ubiquinone oxidoreductase I, membrane subunit N; K00343 NADH-quinone oxidoreductase subunit N; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.937
D920_00578
DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: ctx:Clo1313_3008 1.4e-138 glutamine--scyllo-inositol transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.935
D920_03065
DNA topoisomerase; KEGG: efu:HMPREF0351_10562 0. topB; DNA topoisomerase TopB K03169; Psort location: Cytoplasmic, score: 9.64.
     
 0.932
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.922
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: medium (44%) [HD]