Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01622KEGG: efc:EFAU004_00597 9.3e-39 MazG nucleotide pyrophosphohydrolase; Psort location: Cytoplasmic, score: 7.50. (114 aa)    
Predicted Functional Partners:
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.985
D920_02819
Tetratricopeptide repeat protein; KEGG: bya:BANAU_2226 1.2e-52 ypiA; UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa subunit; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.980
D920_00793
Pyruvate kinase; KEGG: efc:EFAU004_01291 6.6e-299 Pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
    0.974
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.969
D920_00437
Sortase family protein; KEGG: mps:MPTP_0053 1.3e-62 sortase A, LPXTG specific; K07284 sortase A.
       0.962
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
    0.937
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
  
 0.935
D920_03095
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.935
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
       0.930
D920_00099
Helicase protein; KEGG: afm:AFUA_7G05530 7.9e-43 DEAD/DEAH box helicase K01529; Psort location: Cytoplasmic, score: 7.50.
       0.927
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (28%) [HD]