Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01693Glutathione-disulfide reductase; KEGG: efu:HMPREF0351_12682 6.5e-205 gor2; glutathione-disulfide reductase K00383; Psort location: Cytoplasmic, score: 9.97. (449 aa)    
Predicted Functional Partners:
D920_02551
KEGG: efi:OG1RF_11143 4.3e-231 aceF; pyruvate dehydrogenase complex E2, dihydrolipoamide acetyltransferase K00627; Psort location: Cytoplasmic, score: 9.67.
 
 0.998
D920_02552
KEGG: efu:HMPREF0351_11226 1.5e-157 pdhB; pyruvate dehydrogenase complex E1 component beta subunit K00162; Psort location: Cytoplasmic, score: 7.50.
  
 0.997
D920_01697
Negative regulator of genetic competence ClpC/MecB; KEGG: saa:SAUSA300_0510 5.1e-244 clpC; endopeptidase K03696; Psort location: Cytoplasmic, score: 9.95; Belongs to the ClpA/ClpB family.
  
 
 0.995
D920_01694
Peptidase, U32 family; KEGG: efu:HMPREF0351_12683 2.6e-208 U32 family peptidase K08303; Psort location: Cytoplasmic, score: 7.50.
     
 0.993
D920_01695
Peptidase, U32 family; KEGG: efc:EFAU004_02848 4.2e-130 peptidase, U32 family.
     
 0.993
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.990
D920_00407
Glycine cleavage H-protein; KEGG: mpx:MPD5_0506 7.5e-21 arsenate reductase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.989
D920_01698
Putative transcriptional regulator CtsR; Psort location: Cytoplasmic, score: 7.50; Belongs to the CtsR family.
     
 0.989
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.989
D920_02077
KEGG: efi:OG1RF_12271 7.5e-211 cdr; coA-disulfide reductase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.972
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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