Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_01726SNF2 domain protein; KEGG: bao:BAMF_3093 2.4e-143 SWI/SNF chromatin-remodeling complex subunit snf22; Psort location: Cytoplasmic, score: 7.50. (399 aa)    
Predicted Functional Partners:
D920_01725
VRR-NUC domain protein; KEGG: pha:PSHAa1996 0.0017 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.996
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.996
D920_00357
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.989
D920_01722
KEGG: efa:EF0325 0. DNA polymerase; K02334 DNA polymerase bacteriophage-type; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.987
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.986
D920_00099
Helicase protein; KEGG: afm:AFUA_7G05530 7.9e-43 DEAD/DEAH box helicase K01529; Psort location: Cytoplasmic, score: 7.50.
   
 0.979
D920_01727
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.979
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 
 0.979
D920_01715
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.978
D920_01724
Virulence-associated protein E; Psort location: Cytoplasmic, score: 7.50.
 
     0.978
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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