Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_01773Transcriptional regulator, PadR family; KEGG: ase:ACPL_2208 7.5e-05 Coproporphyrinogen 3 oxidase, aerobic. (105 aa)    
Predicted Functional Partners:
D920_01774
Hypothetical protein; KEGG: psb:Psyr_2690 0.0012 glycosyl transferase family protein; K10012 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.999
D920_01775
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.988
D920_00976
KEGG: efc:EFAU004_01514 1.6e-80 CAAX amino terminal protease family protein K07052; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.940
D920_00692
PspC domain protein; KEGG: rer:RER_19410 0.0084 two-component histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55.
       0.932
D920_01770
KEGG: efc:EFAU004_00424 0. ABC transporter ATP-binding protein/permease; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.910
D920_02077
KEGG: efi:OG1RF_12271 7.5e-211 cdr; coA-disulfide reductase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.908
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
       0.904
D920_01237
Protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
       0.904
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
       0.891
D920_01239
DltD protein.
       0.887
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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