Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_01803Cyclic nucleotide-binding domain protein; KEGG: fma:FMG_1494 1.7e-06 pyruvate-formate-lyase-activating enzyme; K04069 pyruvate formate lyase activating enzyme; Psort location: Cytoplasmic, score: 7.50. (214 aa)    
Predicted Functional Partners:
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.992
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.989
D920_01800
Transporter, major facilitator family protein; KEGG: ssr:SALIVB_1450 4.3e-09 coaE; Dephospho-CoA kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.983
D920_01008
Channel protein, MIP family; KEGG: hiq:CGSHiGG_06740 1.7e-23 glpQ; glycerophosphodiester phosphodiesterase K02440; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.976
D920_03105
Channel protein, MIP family; KEGG: hiq:CGSHiGG_06740 2.8e-30 glpQ; glycerophosphodiester phosphodiesterase K02440; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.976
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.966
ecfA-2
ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
 0.964
D920_01520
KEGG: efc:EFAU004_02618 2.5e-242 serine/threonine-protein kinase K08884; Psort location: CytoplasmicMembrane, score: 8.78.
  
  
 0.962
D920_02765
Hypothetical protein; KEGG: ssr:SALIVB_0977 8.2e-15 signal transduction histidine kinase, LytS; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.962
D920_01950
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.957
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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