Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01849Competence protein CoiA-like protein; Psort location: Cytoplasmic, score: 7.50. (299 aa)    
Predicted Functional Partners:
D920_01847
KEGG: efu:HMPREF0351_12421 3.7e-280 pepF; M03 family oligopeptidase F K08602; Psort location: Cytoplasmic, score: 9.97.
     
 0.998
mecA
Negative regulator of genetic competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
 
   
 0.997
D920_01851
ArsC family protein; KEGG: efa:EF2678 1.1e-37 hypothetical protein; K00537 arsenate reductase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ArsC family.
 
   
 0.996
D920_02858
KEGG: apb:SAR116_0616 9.3e-39 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.981
D920_01394
Methyltransferase domain protein; KEGG: efc:EFAU004_00735 1.1e-97 O-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.967
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
       0.966
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.949
D920_00247
HAD hydrolase, family IA, variant 3; KEGG: spa:M6_Spy0549 5.8e-30 Beta-phosphoglucomutase; K01838 beta-phosphoglucomutase K05344; Psort location: Cytoplasmic, score: 7.50.
  
    0.937
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
       0.936
D920_02535
comEA protein; KEGG: has:Halsa_0780 3.1e-08 glycogen/starch synthase K00703; Psort location: CytoplasmicMembrane, score: 9.96.
  
  
 0.931
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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