Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01855Exonuclease SbcCD, C subunit; KEGG: efu:HMPREF0351_12427 2.8e-259 sbcC; exodeoxyribonuclease SbcC K03546; Psort location: Cytoplasmic, score: 9.97. (1040 aa)    
Predicted Functional Partners:
D920_01854
Protein, SNF2 family; KEGG: lml:lmo4a_1704 8.1e-182 Snf2 family helicase; Psort location: CytoplasmicMembrane, score: 8.16.
  
 
 0.999
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.999
D920_00176
KEGG: efc:EFAU004_02529 3.6e-140 Ser/Thr protein phosphatase family protein; Psort location: Cytoplasmic, score: 7.50.
  
 0.997
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.997
D920_01857
Acyltransferase; KEGG: efc:EFAU004_02490 1.1e-92 acyltransferase K00655.
     
 0.995
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.994
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
  
  
 0.992
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.991
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
   
 0.990
rexB
Putative ATP-dependent nuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 2 subfamily.
  
  
 0.989
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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