Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_01859Chloride transporter, ClC family; KEGG: cpr:CPR_1400 7.5e-09 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. (410 aa)    
Predicted Functional Partners:
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.982
D920_00529
Exodeoxyribonuclease III; KEGG: efl:EF62_2889 6.2e-113 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97.
     
 0.963
D920_00947
PTS system mannose-specific EIIBCA component; KEGG: efu:HMPREF0351_11043 1.3e-222 manP; PTS system fructose/mannitol (fru) transporter subunit IIABC; K02793 PTS system, mannose-specific IIA component; K02794 PTS system, mannose-specific IIB component K02795; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.936
D920_01985
PTS system fructose-specific EIIABC component; KEGG: efu:HMPREF0351_11611 4.1e-297 fruAB; PTS system fructose/mannitol (fru) transporter subunit IIABC; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.936
D920_00956
Chorismate mutase; KEGG: efc:EFAU004_00196 1.2e-100 maltose O-acetyltransferase K00661; Psort location: Cytoplasmic, score: 9.67.
  
  
 0.923
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.910
D920_00643
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
     
 0.888
D920_00530
Oxidoreductase, NAD-binding domain protein; KEGG: efc:EFAU004_00657 1.2e-111 oxidoreductase family, NAD-binding Rossmann fold protein K03810; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.885
aspS
aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
     
 0.879
D920_02831
Putative Na+/H+ antiporter; KEGG: tgo:TGME49_105180 2.4e-17 sodium/hydrogen exchanger, putative; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.876
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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