Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_01916Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (535 aa)    
Predicted Functional Partners:
D920_01915
Modification methylase HhaI family protein; KEGG: ssk:SSUD12_0445 3.9e-134 cytosine-specific methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase.
     
 0.985
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.946
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.896
D920_01917
HNH endonuclease domain protein; KEGG: bld:BLi00747 3.6e-21 hypothetical protein; K01157.
       0.892
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
    0.884
D920_03086
Hydrolase, NUDIX family; KEGG: efu:HMPREF0351_10543 1.1e-76 nudF; ADP-ribose diphosphatase K01515; Psort location: Cytoplasmic, score: 7.50.
  
    0.884
D920_00099
Helicase protein; KEGG: afm:AFUA_7G05530 7.9e-43 DEAD/DEAH box helicase K01529; Psort location: Cytoplasmic, score: 7.50.
       0.871
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
       0.868
D920_00181
Protein hit; KEGG: efc:EFAU004_02524 6.1e-58 histidine triad protein K02503; Psort location: Cytoplasmic, score: 7.50.
       0.866
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.855
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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