Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_01917HNH endonuclease domain protein; KEGG: bld:BLi00747 3.6e-21 hypothetical protein; K01157. (223 aa)    
Predicted Functional Partners:
D920_01915
Modification methylase HhaI family protein; KEGG: ssk:SSUD12_0445 3.9e-134 cytosine-specific methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase.
     
 0.960
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.951
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
     
 0.919
D920_00099
Helicase protein; KEGG: afm:AFUA_7G05530 7.9e-43 DEAD/DEAH box helicase K01529; Psort location: Cytoplasmic, score: 7.50.
       0.903
D920_01916
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.892
D920_00129
Hypothetical protein.
     
 0.860
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.860
D920_01726
SNF2 domain protein; KEGG: bao:BAMF_3093 2.4e-143 SWI/SNF chromatin-remodeling complex subunit snf22; Psort location: Cytoplasmic, score: 7.50.
       0.843
D920_01854
Protein, SNF2 family; KEGG: lml:lmo4a_1704 8.1e-182 Snf2 family helicase; Psort location: CytoplasmicMembrane, score: 8.16.
       0.843
D920_01849
Competence protein CoiA-like protein; Psort location: Cytoplasmic, score: 7.50.
       0.833
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.