Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
D920_01987Transcriptional regulator, DeoR family; KEGG: hiq:CGSHiGG_07025 6.4e-24 fucI; L-fucose isomerase K02430. (260 aa)    
Predicted Functional Partners:
D920_01985
PTS system fructose-specific EIIABC component; KEGG: efu:HMPREF0351_11611 4.1e-297 fruAB; PTS system fructose/mannitol (fru) transporter subunit IIABC; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.999
D920_01986
1-phosphofructokinase; KEGG: efu:HMPREF0351_11612 2.0e-130 fruK; 1-phosphofructokinase K00882; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.999
D920_00947
PTS system mannose-specific EIIBCA component; KEGG: efu:HMPREF0351_11043 1.3e-222 manP; PTS system fructose/mannitol (fru) transporter subunit IIABC; K02793 PTS system, mannose-specific IIA component; K02794 PTS system, mannose-specific IIB component K02795; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.997
D920_01603
KEGG: seq:SZO_15270 8.7e-75 tagatose-6-phosphate kinase; K00917 tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.979
D920_01989
KEGG: efu:HMPREF0351_11609 0. pcrA; ATP-dependent DNA helicase PcrA K03657; Psort location: Cytoplasmic, score: 9.67.
  
    0.960
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.948
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.948
D920_01601
Sugar-phosphate isomerase, RpiB/LacA/LacB family; KEGG: efa:EF1834 3.9e-63 lacB; galactose-6-phosphate isomerase subunit LacB K01819; Psort location: Cytoplasmic, score: 7.50.
     
 0.937
D920_01600
KEGG: mps:MPTP_0366 1.0e-41 galactose-6-phosphate isomerase subunit LacA K01819; Psort location: Cytoplasmic, score: 7.50.
     
 0.935
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
       0.928
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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