Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_02034Lipid kinase, YegS/Rv2252/BmrU family; KEGG: efc:EFAU004_01539 1.1e-99 diacylglycerol kinase catalytic subunit K07029; Psort location: Cytoplasmic, score: 7.50. (300 aa)    
Predicted Functional Partners:
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.996
D920_02032
Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.7e-14 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
       0.995
D920_02035
Hypothetical protein; KEGG: ctc:CTC01157 5.3e-07 phosphoesterase K01175; Psort location: CytoplasmicMembrane, score: 9.55.
  
    0.995
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
  
 0.995
D920_02031
Hypothetical protein; KEGG: efc:EFAU004_01542 1.6e-80 SAM-dependent methyltransferase family protein K06967; Psort location: Cytoplasmic, score: 7.50.
       0.990
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
   
 
 0.961
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 0.933
D920_01996
KEGG: efc:EFAU004_01650 8.3e-189 23S rRNA (uracil-5-)-methyltransferase K03215; Psort location: Cytoplasmic, score: 7.50; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
  
 0.922
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.915
D920_00855
Putative 8-amino-7-oxononanoate synthase; KEGG: lgr:LCGT_1810 2.1e-167 2-amino-3-ketobutyrate CoA ligase; K00639 glycine C-acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.913
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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