Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02038Hypothetical protein; KEGG: abs:AZOBR_p350037 0.00072 norB; nitric oxide reductase (NOR), large subunit; K04561 nitric oxide reductase subunit B; Psort location: CytoplasmicMembrane, score: 10.00. (229 aa)    
Predicted Functional Partners:
D920_02039
KEGG: efc:EFAU004_01534 6.4e-63 Nucleoside 2-deoxyribosyltransferase.
       0.997
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.988
D920_01333
Hypothetical protein; KEGG: efu:HMPREF0351_10817 1.3e-126 GNAT family acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.965
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.960
D920_01847
KEGG: efu:HMPREF0351_12421 3.7e-280 pepF; M03 family oligopeptidase F K08602; Psort location: Cytoplasmic, score: 9.97.
       0.932
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.916
D920_03065
DNA topoisomerase; KEGG: efu:HMPREF0351_10562 0. topB; DNA topoisomerase TopB K03169; Psort location: Cytoplasmic, score: 9.64.
 
     0.893
D920_01873
GIY-YIG catalytic domain protein; KEGG: cnc:CNE_2c01410 6.7e-13 cho1; excinuclease Cho K07461.
       0.872
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
     0.870
D920_01117
DNA-binding helix-turn-helix protein; KEGG: mla:Mlab_1603 4.4e-12 adenine deaminase K01486; Psort location: Cytoplasmic, score: 7.50.
     
 0.856
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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