Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02062Hypothetical protein; KEGG: efi:OG1RF_11821 2.9e-19 brp/Blh family beta-carotene 15,15'-monooxygenase; Psort location: CytoplasmicMembrane, score: 10.00. (200 aa)    
Predicted Functional Partners:
mutM
DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.960
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.960
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.960
D920_03139
ATPase, AAA family; KEGG: efu:HMPREF0351_12444 6.9e-201 crossover junction endodeoxyribonuclease K07478; Psort location: Cytoplasmic, score: 7.50.
       0.960
D920_02944
HD domain protein; KEGG: ova:OBV_05350 0.0085 2',3'-cyclic-nucleotide 2'-phosphodiesterase K06950; Psort location: Cytoplasmic, score: 7.50.
       0.944
D920_00940
MATE efflux family protein; KEGG: ssr:SALIVB_2015 2.3e-21 queuine tRNA-ribosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.940
D920_02884
KEGG: apb:SAR116_0013 9.3e-07 BadM/Rrf2 family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
       0.932
D920_03075
Transporter, major facilitator family protein; KEGG: bcz:BCZK2057 9.9e-15 macrolide efflux protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.904
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
       0.891
D920_01465
Aminotransferase, class V; KEGG: efu:HMPREF0351_12189 8.3e-173 iscS2; pyridoxal phosphate-dependent transferase K04487; Psort location: Cytoplasmic, score: 9.97.
       0.890
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.