Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02117TIGR01440 family protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0340 family. (189 aa)    
Predicted Functional Partners:
D920_02116
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.998
D920_02115
KEGG: efu:HMPREF0351_11405 7.2e-71 thiD2; phosphomethylpyrimidine kinase K00868.
       0.997
prmC
protein-(glutamine-N5) methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
      0.986
D920_01600
KEGG: mps:MPTP_0366 1.0e-41 galactose-6-phosphate isomerase subunit LacA K01819; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.985
D920_01601
Sugar-phosphate isomerase, RpiB/LacA/LacB family; KEGG: efa:EF1834 3.9e-63 lacB; galactose-6-phosphate isomerase subunit LacB K01819; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.985
truA-2
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
       0.967
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
       0.967
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.965
D920_02446
Peroxide operon regulator; KEGG: apb:SAR116_1155 2.4e-15 ferric uptake regulation protein K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.
       0.964
D920_01201
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.960
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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