Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02132Pyrimidine nucleoside transport protein; Psort location: CytoplasmicMembrane, score: 10.00. (419 aa)    
Predicted Functional Partners:
D920_01111
KEGG: efc:EFAU004_00077 3.1e-189 pdp; pyrimidine-nucleoside phosphorylase K00756; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.996
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
  
 0.995
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
 0.980
deoD
KEGG: efu:HMPREF0351_10047 1.5e-102 deoD2; purine-nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.97.
     
 0.973
D920_02766
Inosine-uridine preferring nucleoside hydrolase; KEGG: efu:HMPREF0351_12060 3.3e-130 rihB; purine nucleosidase; Psort location: Cytoplasmic, score: 7.50.
     
 0.968
D920_01109
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.965
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.963
tdk
Thymidine kinase; KEGG: efc:EFAU004_02304 1.4e-92 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 9.95.
  
  
 0.958
D920_02307
ABC transporter, substrate-binding protein, QAT family; KEGG: pfe:PSF113_0383 4.1e-61 histidine ABC transporter permease K02001; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.954
D920_02986
KEGG: efc:EFAU004_02230 2.8e-195 Ser/Thr protein phosphatase family protein; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family.
  
  
 0.954
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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