Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02135Transporter, major facilitator family protein; KEGG: fgr:FG00711.1 6.3e-57 hypothetical protein; K10866 DNA repair protein RAD50; Psort location: CytoplasmicMembrane, score: 10.00. (488 aa)    
Predicted Functional Partners:
D920_02136
Putative esterase; KEGG: efu:HMPREF0351_12538 1.5e-116 estA; esterase; K03930 putative tributyrin esterase; Psort location: Extracellular, score: 9.60.
     
 0.997
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.996
D920_02474
CBS domain protein; KEGG: cbj:H04402_01195 9.0e-09 inosine-5'-monophosphate dehydrogenase; Psort location: CytoplasmicMembrane, score: 9.55.
       0.960
D920_02836
Channel protein, hemolysin III family; KEGG: lai:LAC30SC_04890 0.00066 tRNA CCA-pyrophosphorylase K00974; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.956
D920_01576
Transcriptional regulator, PadR family; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.943
D920_02764
Hypothetical protein; KEGG: smz:SMD_1875 2.8e-05 carboxylesterase.
  
  
 0.943
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.931
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.926
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.912
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.854
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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