Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02136Putative esterase; KEGG: efu:HMPREF0351_12538 1.5e-116 estA; esterase; K03930 putative tributyrin esterase; Psort location: Extracellular, score: 9.60. (262 aa)    
Predicted Functional Partners:
D920_02135
Transporter, major facilitator family protein; KEGG: fgr:FG00711.1 6.3e-57 hypothetical protein; K10866 DNA repair protein RAD50; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.997
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.995
D920_02475
Phosphodiesterase family protein; KEGG: efc:EFAU004_01030 1.8e-67 phosphodiesterase K07095; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.990
D920_02075
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.988
D920_00809
Hypothetical protein; KEGG: efc:EFAU004_01232 4.4e-286 ysyl-tRNA synthetase K14205; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.982
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.982
D920_01385
Hypothetical protein; KEGG: pfr:PFREUD_23770 5.9e-37 pf2042; carboxylic ester hydrolase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.973
rnj-2
Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.967
D920_00062
Hypothetical protein; KEGG: dda:Dd703_0763 1.9e-10 PTS system beta-glucoside-specific transporter subunit IIABC; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 9.55.
 
   
 0.963
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.961
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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