Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02169Penicillin-binding protein, 1A family; KEGG: efu:HMPREF0351_12495 0. pbp2A; penicillin-binding protein 2A K12555; Psort location: CytoplasmicMembrane, score: 9.99. (722 aa)    
Predicted Functional Partners:
D920_02170
Hypothetical protein; KEGG: pcb:PC000690.00.0 0.0076 hypothetical protein; K10696 E3 ubiquitin-protein ligase BRE1; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0342 family.
       0.996
D920_02168
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
  
 0.995
gpsB
Putative cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.992
D920_00176
KEGG: efc:EFAU004_02529 3.6e-140 Ser/Thr protein phosphatase family protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.983
D920_00177
Hypothetical protein; KEGG: lru:HMPREF0538_20279 1.0e-54 ppx3; exopolyphosphatase; Psort location: CytoplasmicMembrane, score: 8.16.
       0.979
D920_00178
HDIG domain protein; KEGG: efc:EFAU004_02527 2.9e-154 3'-5' exoribonuclease yhaM K03698; Psort location: Cytoplasmic, score: 7.50.
       0.977
D920_02688
Penicillin-binding protein, transpeptidase domain protein; KEGG: efu:HMPREF0351_10994 0. pbp2B; penicillin-binding protein K00687; Psort location: CytoplasmicMembrane, score: 9.51.
 
 
 0.977
D920_02266
Putative penicillin-binding protein 3; KEGG: efc:EFAU004_00870 1.5e-212 penicillin binding protein transpeptidase domain protein; Psort location: CytoplasmicMembrane, score: 9.51.
 
 
 0.971
D920_01360
KEGG: efu:HMPREF0351_10791 0. pbpA; penicillin-binding protein 1 K12556; Psort location: CytoplasmicMembrane, score: 9.51.
 
 
 
0.970
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
  
 0.965
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.