Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uxaCGlucuronate isomerase; KEGG: efu:HMPREF0351_12490 8.0e-207 uxaC; glucuronate isomerase K01812; Psort location: Cytoplasmic, score: 7.50. (463 aa)    
Predicted Functional Partners:
D920_02185
KEGG: efu:HMPREF0351_12488 2.6e-176 mannitol dehydrogenase K00041; Psort location: Cytoplasmic, score: 9.95.
 
  
 0.999
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.999
D920_02617
Mannitol dehydrogenase domain protein; KEGG: efu:HMPREF0351_11449 7.3e-181 uxuB; fructuronate reductase K00040; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.999
D920_02186
SAF domain protein; KEGG: efu:HMPREF0351_12489 9.9e-225 uxaA; altronate dehydratase K01685; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.998
D920_00885
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; KEGG: efc:EFAU004_00253 7.8e-90 keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase K01625; Psort location: Cytoplasmic, score: 9.67.
 
   
 0.995
mtlD
KEGG: efa:EF0413 7.5e-140 mtlD; mannitol-1-phosphate 5-dehydrogenase; K00009 mannitol-1-phosphate 5-dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.993
kduI
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.988
D920_02618
Transcriptional regulator, GntR family; KEGG: cnc:CNE_2c19120 2.7e-09 phnA2; phosphonoacetate hydrolase PhnA; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.987
D920_00454
Kinase, PfkB family; KEGG: efi:OG1RF_10571 4.1e-100 PfkB family carbohydrate kinase; K00874 2-dehydro-3-deoxygluconokinase; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.982
D920_00884
Kinase, PfkB family; KEGG: efu:HMPREF0351_10219 2.7e-135 kdgK; 2-dehydro-3-deoxygluconokinase K00874; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.982
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.