Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02307ABC transporter, substrate-binding protein, QAT family; KEGG: pfe:PSF113_0383 4.1e-61 histidine ABC transporter permease K02001; Psort location: CytoplasmicMembrane, score: 10.00. (570 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.999
D920_02308
KEGG: efc:EFAU004_02434 4.5e-181 glycine betaine transporter ATP-binding subunit K02000; Psort location: CytoplasmicMembrane, score: 9.96.
 
 
 0.999
D920_02309
KEGG: bya:BANAU_2956 0.00013 ytrA; GntR family transcriptional regulator; Psort location: CytoplasmicMembrane, score: 8.16.
 
   
 0.999
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.998
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.998
D920_02613
KEGG: efi:OG1RF_10412 2.1e-158 ABC superfamily ATP binding cassette transporter, membrane protein K05845:K05846; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
0.997
D920_02736
Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
       0.989
D920_02683
Periplasmic binding protein; KEGG: bao:BAMF_3696 1.1e-19 RBAM_035840; iron compound ABC transporter substrate-binding protein FeuA K02016; Psort location: CytoplasmicMembrane, score: 9.68.
     
 0.987
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.987
D920_00913
KEGG: efi:OG1RF_10592 1.1e-97 opuCD; glycine/betaine/carnitine/choline ABC superfamily ATP binding cassette transporter, membrane protein K05846; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.984
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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