Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02346KEGG: cfu:CFU_1514 7.3e-07 TetR family transcriptional regulator K16137; Psort location: Cytoplasmic, score: 9.97. (203 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.936
D920_01579
Nitroreductase family protein; KEGG: efu:HMPREF0351_12619 1.3e-89 NADH dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.913
D920_00918
Phage infection protein; KEGG: edi:EDI_048910 2.3e-14 intracellular protein transport protein USO1; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.881
D920_01770
KEGG: efc:EFAU004_00424 0. ABC transporter ATP-binding protein/permease; Psort location: CytoplasmicMembrane, score: 10.00.
   
 
 0.881
D920_02143
Efflux ABC transporter, permease protein; KEGG: ljf:FI9785_1686 1.1e-49 ABC transporter permease K02004; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.879
D920_02348
Isochorismatase family protein; KEGG: efu:HMPREF0351_10514 7.0e-89 entB2; isochorismatase; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.839
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.837
D920_02144
ABC transporter, ATP-binding protein; KEGG: efi:OG1RF_10527 8.4e-93 ABC superfamily ATP binding cassette transporter, ABC protein K02003; Psort location: CytoplasmicMembrane, score: 8.78.
   
 
 0.834
D920_02243
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.829
D920_00135
YD repeat protein; KEGG: phu:Phum_PHUM617500 0.0010 type II transmembrane protein, putative; Psort location: Cellwall, score: 9.20.
  
  
 0.824
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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