Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02370Methyltransferase domain protein; KEGG: ckl:CKL_2616 2.2e-85 methyltransferase; Psort location: Cytoplasmic, score: 7.50. (244 aa)    
Predicted Functional Partners:
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.980
D920_01675
Polyprenyl synthetase; KEGG: efu:HMPREF0351_12674 1.8e-136 hepT; trans-hexaprenyltranstransferase K00805; Psort location: Cytoplasmic, score: 9.97; Belongs to the FPP/GGPP synthase family.
  
 
 0.980
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.972
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.947
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
 0.944
D920_00956
Chorismate mutase; KEGG: efc:EFAU004_00196 1.2e-100 maltose O-acetyltransferase K00661; Psort location: Cytoplasmic, score: 9.67.
 
  
 0.939
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.933
D920_00465
Nucleoside diphosphate kinase; KEGG: efu:HMPREF0351_10641 1.6e-50 ndk; nucleoside-diphosphate kinase K00940; Psort location: Cytoplasmic, score: 9.97; Belongs to the NDK family.
  
 
 0.928
D920_01312
Glycosyltransferase, group 2 family protein; KEGG: efu:HMPREF0351_10905 0. family 2 glycosyl transferase; Psort location: CytoplasmicMembrane, score: 8.78.
  
  
 0.926
D920_01685
KEGG: efu:HMPREF0351_12681 1.2e-125 UbiA family prenyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.926
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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