Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02400Carbonate dehydratase, eukaryotic-type; KEGG: efc:EFAU004_00960 5.1e-86 carbonic anhydrase K01674; Psort location: Cytoplasmic, score: 7.50. (233 aa)    
Predicted Functional Partners:
D920_02399
KEGG: mct:MCR_0286 1.2e-10 LysR family transcriptional regulator K04761; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
     
 0.997
D920_01804
Hydrolase, alpha/beta domain protein; KEGG: cbj:H04402_00528 9.0e-57 lysophospholipase; Psort location: CytoplasmicMembrane, score: 8.16.
     
 0.984
D920_02713
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.962
D920_02401
HD domain protein; KEGG: tau:Tola_2690 2.3e-12 metal dependent phosphohydrolase K08722; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.959
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
     
 0.933
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
 
 0.907
D920_01278
KEGG: efc:EFAU004_01339 6.5e-54 GNAT family acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.906
D920_01257
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.904
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
       0.904
D920_02945
RNA methyltransferase, TrmH family; KEGG: efc:EFAU004_01939 7.1e-96 RNA methyltransferase K03437; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.898
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.