Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02401HD domain protein; KEGG: tau:Tola_2690 2.3e-12 metal dependent phosphohydrolase K08722; Psort location: Cytoplasmic, score: 7.50. (225 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.971
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
  
    0.967
D920_02399
KEGG: mct:MCR_0286 1.2e-10 LysR family transcriptional regulator K04761; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
     
 0.966
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.965
D920_02984
HAD hydrolase family; KEGG: efu:HMPREF0351_12211 1.9e-109 HAD superfamily hydrolase.
  
  
 0.960
D920_02400
Carbonate dehydratase, eukaryotic-type; KEGG: efc:EFAU004_00960 5.1e-86 carbonic anhydrase K01674; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.959
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.952
D920_02457
KEGG: efc:EFAU004_01014 1.2e-269 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
     
 0.949
D920_00719
Phosphoglucomutase; KEGG: efc:EFAU004_02002 3.6e-259 phosphoglucomutase/phosphomannomutase family protein K01835; Psort location: Cytoplasmic, score: 7.50.
       0.947
D920_00690
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
       0.945
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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