Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02412Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (301 aa)    
Predicted Functional Partners:
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
  
  
 0.998
pyrR
Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
  
  
 0.996
D920_02414
CBS domain protein; Psort location: Cytoplasmic, score: 7.50.
       0.996
D920_02415
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.996
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.993
pyrB
KEGG: efc:EFAU004_00969 9.8e-154 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.993
fhs
KEGG: ehr:EHR_12175 2.0e-242 formate--tetrahydrofolate ligase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.993
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
   0.991
D920_02420
Major cold shock protein CspA; KEGG: apb:SAR116_2174 4.2e-11 cold-shock DNA-binding domain-containing protein K03704; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.990
D920_02410
Uracil permease; KEGG: hiq:CGSHiGG_01870 2.2e-78 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.989
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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