Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
D920_02423Cation diffusion facilitator family transporter; KEGG: msi:Msm_0789 3.8e-33 cation efflux system protein (zinc/cadmium/cobalt); Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (375 aa)    
Predicted Functional Partners:
D920_00918
Phage infection protein; KEGG: edi:EDI_048910 2.3e-14 intracellular protein transport protein USO1; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.995
D920_02774
Putative cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
    0.992
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.974
D920_02457
KEGG: efc:EFAU004_01014 1.2e-269 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
       0.974
D920_01989
KEGG: efu:HMPREF0351_11609 0. pcrA; ATP-dependent DNA helicase PcrA K03657; Psort location: Cytoplasmic, score: 9.67.
  
    0.969
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.961
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.960
D920_02459
Hypothetical protein; KEGG: edi:EDI_048910 0.00014 intracellular protein transport protein USO1; Psort location: CytoplasmicMembrane, score: 9.55.
       0.960
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.956
D920_01988
Chloride transporter, ClC family; KEGG: ssr:SALIVB_1179 3.8e-113 ribonuclease HII; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.946
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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