Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
recURecombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (220 aa)    
Predicted Functional Partners:
gpsB
Putative cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
   
 0.999
D920_02441
Penicillin-binding protein, 1A family; KEGG: efu:HMPREF0351_11323 0. ponA; peptidoglycan glycosyltransferase K05366; Psort location: CytoplasmicMembrane, score: 8.77.
 
  
 0.999
D920_02439
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0398 family.
 
  
 0.997
rsmG
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
     
 0.986
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.983
D920_02025
Primosomal protein DnaI; Psort location: CytoplasmicMembrane, score: 8.16.
 
   
 0.978
nfo
Apurinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
 
  
 0.966
D920_02169
Penicillin-binding protein, 1A family; KEGG: efu:HMPREF0351_12495 0. pbp2A; penicillin-binding protein 2A K12555; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.965
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
  
 0.963
D920_02443
DnaD domain protein; KEGG: ssr:SALIVB_1214 1.6e-11 tpiA; triosephosphate isomerase K02086; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.955
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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