Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02443DnaD domain protein; KEGG: ssr:SALIVB_1214 1.6e-11 tpiA; triosephosphate isomerase K02086; Psort location: Cytoplasmic, score: 7.50. (192 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 0.999
D920_02025
Primosomal protein DnaI; Psort location: CytoplasmicMembrane, score: 8.16.
 
  
 0.998
D920_02446
Peroxide operon regulator; KEGG: apb:SAR116_1155 2.4e-15 ferric uptake regulation protein K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.
     
 0.992
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
 
  
 0.992
D920_02436
Carboxypeptidase Taq metallopeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
       0.991
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.990
D920_02444
NADH oxidase; KEGG: efc:EFAU004_01004 8.6e-210 nox; NADH oxidase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.988
D920_00368
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
  
 0.985
D920_02451
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.983
D920_02457
KEGG: efc:EFAU004_01014 1.2e-269 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.982
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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