Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_02444NADH oxidase; KEGG: efc:EFAU004_01004 8.6e-210 nox; NADH oxidase; Psort location: Cytoplasmic, score: 9.97. (450 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
     
 0.991
D920_02443
DnaD domain protein; KEGG: ssr:SALIVB_1214 1.6e-11 tpiA; triosephosphate isomerase K02086; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.988
D920_02446
Peroxide operon regulator; KEGG: apb:SAR116_1155 2.4e-15 ferric uptake regulation protein K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.
     
 0.988
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.977
D920_01286
Superoxide dismutase, Mn; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.975
D920_03104
KEGG: efc:EFAU004_00496 3.4e-135 FAD dependent oxidoreductase.
  
 
 0.974
D920_02522
Metallo-beta-lactamase domain protein; KEGG: efu:HMPREF0351_11255 9.2e-87 gloB; hydroxyacylglutathione hydrolase.
  
 0.973
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.968
D920_01579
Nitroreductase family protein; KEGG: efu:HMPREF0351_12619 1.3e-89 NADH dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.952
D920_02448
Cysteine synthase A; KEGG: efc:EFAU004_01006 6.6e-132 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 7.50; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.951
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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