Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02448Cysteine synthase A; KEGG: efc:EFAU004_01006 6.6e-132 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 7.50; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)    
Predicted Functional Partners:
D920_01562
KEGG: efu:HMPREF0351_12603 1.9e-77 cysE; serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.999
cysS
cysteine--tRNA ligase; KEGG: efc:EFAU004_02655 1.8e-223 cysS; cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.996
D920_02446
Peroxide operon regulator; KEGG: apb:SAR116_1155 2.4e-15 ferric uptake regulation protein K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.
  
  
 0.994
D920_02599
Ornithine cyclodeaminase/mu-crystallin family protein; KEGG: efu:HMPREF0351_12084 1.9e-102 ornithine cyclodeaminase K01750; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.994
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.993
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
  
  
 0.993
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
 0.993
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.992
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.988
ftsH
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 
 0.988
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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